Endocrine Abstracts

Background/objective: mETE has shown no effect on survival, and the 8th edition of the AJCC classification no longer considers mETE in the pT3 definition. Therefore, tumors with mETE below 40 mm are now staged pT1/pT2. However, controversy remains regarding mETE impact on disease recurrence. This study assessed the risk of recurrence of PTC patients previously classified as pT3 because of mETE, compared to PTC patients staged pT1-pT2.Methods: Monocentric...

Introduction: Genetic of pituitary tumors (PT) is incompletely understood. The aim of this study was to search for somatic copy number variations (CNV) in pituitary tumors and evaluate their prognostic impact on tumor recurrence.Methods: CGH array analysis (Agilent SurePrint G3 Human CGH+SNP Microarray 4×180 K) was performed on 196 fresh-frozen PT (67 gonadotroph, 31 corticotroph, 38 prolactinomas, 60 somatotroph). PT were classified according to th...

Thyroid nodules are very common and benign in most cases. Thus, malignancy detection avoiding overtreatment is a challenge. Nodule evaluation mainly supports on US and fine needle aspiration cytology (FNAC). The Bethesda classification (BC) for reporting thyroid cytopathology is now currently used for the interpretation of results but it does not enable classifying 30% of samples.The objective was to identify, by transcriptome analysis, a molecular signa...